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Process Development (UPSTREAM) Team Lead

Job Posted: 10 days ago

  • Salary: £ 60,000 - 70,000 / Annum

    Job Type: Permanent

  • Location: London

Expire in: 17 days

Job Description

Walker Cole International is hiring for an experienced Upstream Bioprocessing lead to join a growing biopharma company in West London and help mentor and grow their USP team. You’ll lead a small team overseeing cell culture and upstream process development, optimising mammalian processes in ambr250 and small-scale bioreactors to support high-quality protein and antibody production. Key responsibilities: * Manage daily cell culture operations, including revival, subculture, cryopreservation, sampling, and in-process analysis. * Monitor and optimise culture conditions, track outputs, and troubleshoot technical issues. * Analyse data, report results, and maintain SOPs, risk assessments, COSHH, and DoEs. * Collaborate with UK and international colleagues on process development projects. * Ensure equipment is maintained and processes run efficiently. You’ll need: * Experience in mammalian cell culture process development, ideally using automated bioreactors. * Knowledge of GLP/GMP standards, safety audits, and risk assessments. * Understanding of therapeutic protein/antibody quality attributes. * Strong communication, leadership, and problem-solving skills. * A Masters or PhD in Biological Science or related field. Cell Culture | Bioprocess Development | Bioreactors | Team Leadership | GMP | Antibody Production | Biosimilars | Upstream

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