Hiring Now: Senior Scientist Phage Display Near You – Apply Today!
Your Next Senior Scientist Phage Display Job Starts Here – Apply Now!
Senior Scientist Phage Display
Job Posted: 9 days ago
Salary: £ Competitive
Job Type: Permanent
Location: Cambridge
Expire in: 19 days
Job Description
CK Group are working in partnership with Nxera Pharma UK Limited (formerly Sosei Heptares) to recruit a lab-based Senior Scientist position in the Protein Binder Discovery team based in Granta Park, Cambridge.
Company:
Nxera Pharma is a technology powered biopharma company, in pursuit of new specialty medicines to improve the lives of patients with unmet needs in Japan and globally, focused on therapeutic areas in inflammation diseases, neurology and immunology.
The Role:
We are searching for an experienced phage display scientist to join the Protein Binders team, part of our Platform Technology division at Nxera Pharma. The successful candidate will use phage display expertise to identify and characterise protein binders against therapeutic membrane protein targets to enable structure determination and drug discovery efforts. The candidate will work in interdisciplinary teams in a project-centric fashion, with the aim of accelerating the development of life-changing medicines.
The role will include the following responsibilities:
Employing phage display technology to select protein binders against membrane protein targets
Screening and validating hits using high-throughput assays e.g. ELISA formats, BLI, cell binding assays
Assay development for challenging targets
Subcloning of plasmid constructs for expression and protein engineering of antibody frameworks
Biophysical evaluation of VHH hits
Sharing your expertise, insights, and ideas with the team, and department to positively influence project success.
Lab management to ensure equipment is regularly maintained and consumables organised efficiently
Effective management of large datasets formulated for ease of sharing data
Requirements:
PhD (or MSc/MRes with equivalent lab experience) in a relevant area of biology with at least 3-years experience carrying out phage display campaigns
Theoretical and practical expertise in phage display technologies and selection techniques
Experience working with phage antibody libraries and preferably VHH display
Strong and evidenced molecular biology proficiency
Demonstrable expertise in protein-protein interaction screening techniques
Dynamic, analytical thinker with good problem-solving skills
Have strong interpersonal skills and interact effectively with scientists across disciplines to generate timely and informative data.
Desirables:
Measuring protein binder affinity using either BLI or SPR
Affinity maturation
Library build (either affinity maturation or immunised, naïve or synthetic libraries)
Working with membrane proteins (in particular GPCRs)
Computational expertise in protein binder design
Apply:
Please quote job reference (Apply online only) in all correspondenceBefore You Apply
Do not include the following in your job application, CV, or cover letter:
- Bank details.
- National Insurance number.
- Date of birth.
You should not be asked for payment or irrelevant information. If you have concerns about a job advert or employer, seek guidance on how to proceed.
Looking for your next career move? Join a top company hiring Senior Scientist Phage Display job near me in Cambridge! This is your chance to work on exciting projects, grow professionally, and enjoy a rewarding career with competitive pay and excellent benefits. Whether you're an experienced professional or looking to take the next step, this role offers the perfect opportunity to enhance your skills and make an impact. Don’t miss out—apply today via Vita CV and take your career to the next level!
© Vita CV: Registered in England and Wales (16187919).